The three proteins with the highest coefficients were hemopexin, fibulin-1, and cystatin C. The heme-binding glycoprotein hemopexin plays a key role in protecting LDL [49] and neurons [50] from oxidative stress and is enriched in amyloid deposits in the brains of Alzheimer’s Disease (AD) patients [51]. The gene discussed is HPX; the disease is early-onset autosomal dominant Alzheimer disease.