Surprisingly, the deeper insight at protein level showed significant increased CACNB3 expression levels (immunoreactivity) in all temporal lobe neocortical layers compared to non-epilepsy control subjects, while KCNH5 and KCNH7 had showed increased expression levels in the first layer only (Fig. 3A; Fig SI21-25). This evidence concerns the gene KCNH7 and epilepsy.