GNRH1 and colorectal carcinoma: Stratified into different forms of ADT, there was a significantly increased risk of developing CRC after exposure to AA (HR 1.23 [95% CI 1.04–1.47]) and GnRH + flare (HR 1.22 [95% CI 1.04–1.43]), an increased point estimate but not a significantly increased risk of developing CRC after exposure to GnRH (HR 1.30 [95% CI 0.98–1.72]) or Orchiectomy (HR 1.39 [95% CI 0.95–2.03]), whilst exposure to Total Androgen Blockade (TAB) yielded a decreased point estimate that was not significant (HR 0.87 [95% CI 0.43–1.75]).