As previously shown in Fig. 4, infection with the 2_87 Vpu virus resulted in increased levels of p-p105 in untreated cells, and this was much more pronounced upon treatment with TNFα; for the S3/7A and NL4.3 viruses, p-p105 levels were similar to uninfected cells upon treatment. The gene discussed is NFKB2; the disease is infection.