Emerging compounds targeting key regulators of ferroptosis to attenuate AD (7,8‐DHF, 7,8‐Dihydroxyflavone; ACSL4, long‐chain acyl‐CoA synthetase 4; DHMDC, 2′,6′‐dihydroxy‐4′‐methoxy dihydrochalcone; DMT1, iron importer divalent metal transporter 1; FPN1, iron efflux transporter; FSP1, ferroptosis suppressor protein 1; FTH1, Ferritin Heavy Chain 1; N2L, a novel lipoic acid‐niacin dimer; OABL, 1,6‐O,O‐diacetylbritannilactone; TFR2, iron uptake transporter; TSG, Tetrahydroxy stilbene glycoside; γ‐GC,γ‐glutamylcysteine). This evidence concerns the gene ACSL4 and Alzheimer disease.