Ample evidence has shown that aberrant levels of iron regulatory molecules, such as elevated CSF ferritin,[153] hepcidin,[154] Tf (iron transport),[155, 156] ferritin (iron storage), and decreased ferroportin (Fpn, iron export),[157, 158] are associated with the pathogenesis of AD. The gene discussed is SLC40A1; the disease is Alzheimer disease.