ANO1 and neoplasm: On protein level, immunohistochemistry staining of 70 surgically resected GC cases (representatively in Figure S2D, Supporting Information) indicated evidently higher ANO1's positive rate in tumor than in normal tissue (38.6% vs 12.5%, Figure S2E, Supporting Information), while similar result was observed in another 30 GC cases (33.3% vs 23.3%, Figure S2F, Supporting Information) from a tissue microarray.