Ras mutation has been proven to be related to human pituitary tumors, and H‐ras point mutation has been found in distant metastatic pituitary cancer, which indicates that H‐ras gene mutation may play an important role in the formation of pituitary cancers and the metastasis of PitNETs.31, 35, 36. The gene discussed is HRAS; the disease is pituitary cancer.