Among candidate genes, LRP10 was ranked as a top KND of the female AD network with a score of 0.941 (the range of score is between 0 (the least important) and 1 (the most important; Fig. 3A; Fig. 2C and D; Supplemental Tables 10–11) and thus was prioritized for validation studies. The gene discussed is LRP10; the disease is Alzheimer disease.