ERBB2 and non-small cell lung carcinoma: Most of the previous studies on Her2 expression in NSCLC defined the IHC positivity based only on the membranous staining, and many considered scores of 2 + and 3 + as positive, regardless of FISH results, so they reported a higher frequency of overexpression; however, when considering a score of 3 + as positive, they found a comparable rate to ours [17, 35].