Furthermore, the effect of different viral responses on 1-year OS and 1-year PFS were analyzed in the different categories of etiologies (cirrhosis or no cirrhosis), HBV DNA (high or low), serum ALT (> 50 U/L or ≤ 50 U/L) level, and HBeAg (positive or negative) status. Here, GPT is linked to Cirrhosis.