According to the DEG expression analysis, FZD1, GPR37, IL10, LRRK2, MELK, MET, NOL3, P4HB, PDK1, PML, PYCR1, RACK1, SOD2, and TLR6 were highly expressed in ccRCC neoplastic tissues compared with peritumoral tissues (P < 0.05, Fig. 1B). Here, LRRK2 is linked to nonpapillary renal cell carcinoma.