BDNF and post-traumatic stress disorder: Maurel et al. [75] evaluated the expression of FK506 binding protein 5 (FKBP5), BDNF, and a set of miRNAs targeting both FKBP5 and BDNF and observed lower transcript levels of miR-15a-5p, miR-497a-5p, and miR-511a-5p in the hippocampus and hypothalamus of PTSD-related susceptible mice, compared with resilient mice when subjected to the Arousal-Based Individual Screening (AIS), which is a novel PTSD animal model, and is specifically designed for trauma susceptibility and resilience research [76].