TNF and hydrops fetalis: Some notable inflammatory biomarkers in HF include tumour necrosis factor alpha (TNF-a), interleukin 1 (IL-1), interleukin-6 (IL-6), interleukin-8 (IL-8), myeloperoxidase (MPO), inducible nitric oxide synthase (iNOS), and c-reactive protein (CRP) [3].