ACTA1 and Klebsiella pneumonia: To determine whether the interplay of MoMFs, SOX9+ hepatocytes, and aHSCs also applies to other models of liver injury, we performed immunohistochemistry analyses of IBA1, SOX9, and α-SMA in several liver-injury models induced by Klebsiella pneumoniae (KP) infection, ischemia/reperfusion (I/R), or hepatic toxins (carbon tetrachloride [CCl4], and APAP).