CACNA1C and bipolar disorder: Multiple genome-wide association studies point to variants in the CaV1.2 gene, CACNA1C, as major risk factors for schizophrenia, bipolar disorder, and other mental diseases (Bhat et al., 2012; Ferreira et al., 2008; Green et al., 2010; Nyegaard et al., 2010; Smoller, 2013; Splawski et al., 2004).