TLR2 and Alzheimer disease: TLR2 is the primary receptor for innate recognition of gram‐positive bacteria, including S. aureus (Takeuchi et al., 1999), with an important role during CD1a‐mediated T cell responses (Hardman et al., 2017); its polymorphism has been shown in AD previously (Tesse et al., 2011) and linked with the disease severity as well as other allergic manifestations (Potaczek et al., 2011).