TLR2 is the primary receptor for innate recognition of gram‐positive bacteria, including S. aureus (Takeuchi et al., 1999), with an important role during CD1a‐mediated T cell responses (Hardman et al., 2017); its polymorphism has been shown in AD previously (Tesse et al., 2011) and linked with the disease severity as well as other allergic manifestations (Potaczek et al., 2011). The gene discussed is CD1A; the disease is Alzheimer disease.