The results showed that the expression of p-AMPK (P < 0.0001, versus sham group) and HNF4α (P < 0.001, versus sham group) decreased synchronously after CA; at the same time, the expression of the anti-apoptotic factor Bcl-2 (P < 0.001, versus sham group) decreased, and the expression levels of the pro-apoptotic factors Bax (P < 0.0001, versus sham group) and Cleaved-Caspase 3 (P < 0.0001, versus sham group) increased. Here, HNF4A is linked to cancer.