Immunohistochemical CD117/KIT overexpression correlated significantly with schistosomiasis association with a P value = 0.01, where 26 cases (86.67%) out of the 30 schistosomiasis-related urinary bladder carcinoma and 17 (56.67%) out of 30 control (non-schistosomiasis related urinary bladder carcinomas were CD117/KIT positive. This evidence concerns the gene KIT and urinary bladder carcinoma.