We found that the mutation consistency of the four driver genes (TERT promoter, TP53, CTNNB1, and AXIN1) between the tumor tissues and the preoperative CTCs was 93.75% (15/16), 71.43% (30/42), 92.31% (12/13), and 62.50% (5/8), respectively, both were considerable (Figure 2B; Table S4). The gene discussed is AXIN1; the disease is neoplasm.