For symptomatic anemia related to variceal bleeding in cirrhosis transfusion is given for Hb less than 7 g/dL and maintaining the level between 7 and 9 g/dL has been shown to improve survival in Child-Pugh A and B cirrhosis as well as decrease rebleeding risk [42-44]. The gene discussed is GSTM1; the disease is anemia (phenotype).