BMI: body mass index; MI: myocardial infarction; COPD: chronic obstructive pulmonary disease; BNP: B-type natriuretic peptide; CTR: cardiothoracic ratio; LA: left atrial; LVIDD: left ventricular internal diameter at end-diastole; LVEF: left ventricular ejection fraction; DVD: double vessel disease; TVD: triple vessel disease: RCA: right coronary artery. This evidence concerns the gene NPPB and glycogen storage disease VI.