CFTR and colorectal cancer: GEO survival analysis was conducted to screen TCF4 target genes associated with the survival of colorectal cancer patients, among which Cystic fibrosis transmembrane conductance regulator (CFTR), Tyrosine-protein kinase Fyn (FYN), and YOD1 deubiquitinase (YOD1) were considered to be eligible (Fig. 3F, Table S1).