Highly expressed PSMD2 and SMD14 were greatly related to lymph node metastases and TNM phase of lung adenocarcinoma [32, 33], while high expression of PSMD2, PSMD7, PSMD14 were linked to poor OS and/ or disease-free survival (DFS) among these patients [30, 32, 33]. This evidence concerns the gene PSMD2 and metastatic malignant neoplasm in the lymph nodes.