To assess the role of PSMD3 in tumor development in vivo, Ctrl, pcDNA3.1-PSMD3 overexpression plasmids (PSMD3 groups) or/and ILF3 inhibitor YM155 (PSMD3 + YM155), transfected A549 cells were used in tumor xenograft model mice. Here, PSMD3 is linked to neoplasm.