This revealed that PCOS itself could not increase OS, ascorbate could increase the occurrence of PCOS, and the increase in the oxidative level of PCOS was related to other potential factors, such as testosterone, low-density lipoprotein, high-density lipoprotein, sex hormone-binding globulin, body mass index, triacylglycerol, and age at menarche, which may act as characteristic indices of PCOS. Here, SHBG is linked to polycystic ovary syndrome.