In another study, Hesami et al. conducted a double-blind, placebo-controlled clinical trial on type 2 diabetic patients and reported that in the propolis group compared to the placebo, the level of oxidized low-density lipoprotein cholesterol (Ox-LDL-C) reduced and catalase (CAT) activity improved significantly23. The gene discussed is CAT; the disease is type 2 diabetes mellitus.