MAGEA3 and neoplasm: However, a promising new research was observed that abscopal is associated with products of tumor-associated gene expression as autoantibodies (aTAAs) in reaction to the tumor-associated antigens (TAAs), with increasing of anti-MAGEA3 after localized radiation therapy, and an relationship between the abscopal effect and an immune response, reappearance and immune response to the system is called abscopal effect which may eventually help us understand the key to metastatic cancer and find a way of how to reduce and treat the potentially metastasis of cancer2–5.