Furthermore, extending the MYC–WDR5 connection to additional cancers such as those maintained by N-MYC overexpression would bolster the idea that WDR5 is a context-independent MYC recruiter [10] and may allow a prediction to be made as to how targeting WDR5 in cancer would impact MYC binding to chromatin regardless of cancer context [11]. This evidence concerns the gene MYC and cancer.