CD4 and Uterine leiomyoma: However, no difference was observed of MCT-positive mast cells and CD45-positive leukocytes between uterine leiomyomas and normal tissues.[32] The number of circulating follicular helper T cells (Tfh), regulatory T cells (Treg, CD4 +) and CD4 + CD8 + T cells in patients increased significantly, while the number of T cells (CD4-CD8-) and natural killer cells (NK) decreased.[33] In our study, using the CIBERSORT analysis tool, we analyzed the content and percentage of 22 immune cells in uterine fibroids.