In KEGG analysis, DEGs are mainly enriched in PI3K-Akt signaling pathway, Focal adhesion, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Ras signaling pathway, Regulation of actin cytoskeleton, Rap1 signaling pathway, Fluid shear stress and atherosclerosis, cAMP signaling pathway and Tight junction. This evidence concerns the gene AKT1 and atherosclerosis.