Although there are relatively few case studies on COVID-19 with systemic lupus erythematosus (SLE), we found some clues about a potential association between the 2 in the study by Najafi et al[10] Elevated levels of IL-17, IL-23, IFN-α, and γ in patients with SLE are often the cause of severe clinical symptoms in patients, and these factors also influence the prognostic status of patients with COVID-19. This evidence concerns the gene IL17A and COVID-19.