EGFR and ovarian carcinoma: The oxidation products of stigmasterol interfere with the female sex hormone 17β-estradiol in human breast and endometrial cells.[47] Stigmasterol Causes Ovarian Cancer Cell Apoptosis by Inducing Endoplasmic Reticulum and Mitochondrial Dysfunction.[48] Stigmasterol is also a potential metabolic regulator of neurodegenerative diseases.[49] BHDH Decoction may treat MS through possible signaling pathways, including endocrine resistance, the ErbB signaling pathway, Hepatitis B, Progesterone-mediated oocyte maturation, and the relaxin signaling pathway.