A total of 238 pathways were obtained by KEGG enrichment analysis (P < .01), and the top 25 pathways from small to large according to P values are shown in Figure 6 A, including endocrine resistance, pathways in cancer, prostate cancer, ErbB signaling pathway, Hepatitis B, Progesterone-mediated oocyte maturation, relaxin signaling pathway, proteoglycans in cancer, prolactin signaling pathway, and pancreatic cancer. This evidence concerns the gene PRL and prostate carcinoma.