We found a strong link with disease staging, similar to how Elyasinia et al[58] found a higher NLR ratio with a higher clinical stage, but in contrast, they found no significant relationship with ER, PR, or HER2/neu.[29] Our results also negate the study of Yilmaz et al[59] who claimed no significance between preoperative NLR with breast cancer subtypes. Here, ESR1 is linked to breast cancer.