TNF and sexually transmitted disease: Fortunately, studies have shown that treatment with “San Jiao” acupuncture (CV6 + CV12 + CV17 + SP10 + ST36 + SJ5) can significantly increase the levels of anti-inflammatory substances, such as T lymphocytes, in the peripheral blood and significantly decrease the amount of pro-inflammatory factors, such as TNF-α, in the blood, in addition to a decreasing trend in the levels of IL-1β and IL-2.[61] The conclusions drawn from acupuncture to improve VD animal models are just effective in promoting clinical practice.