Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease and is primarily characterized by the accumulation of excess lipids in the liver.[6,7] Obesity is a key factor in the development of NAFLD.[8] Some studies have also found that particular tumor necrosis factors are also closely related to the progression of NAFLD.[9,10] At present, effective NAFLD treatments and interventions have not yet been developed.[11]. Here, TNF is linked to metabolic dysfunction-associated steatotic liver disease.