CYBB and liver disorder: Nonalcoholic steatohepatitis (NASH) is characterized by steatosis, liver cell damage, and inflammation and is an advanced form of NAFLD.[41] CYBB can be mediated by the gene regulator TAZ in NASH hepatocytes, resulting in oxidative DNA damage, which in turn affects the progression of liver disease.[42] In this study, GO and KEGG enrichment analysis showed that CYBB was related to immune response and Osteoclast differentiation.