For the sake of clarifying the expression of BMGs in glioma, this study screened 9 BMGs that were upregulated in glioma (FBN2, FREM3, Lamb4, MEP1A, MMP1, MMP7, OPTC, EVA1A, and ADAMTS20) from TCGA -GTEX expression matrix. The gene discussed is FREM3; the disease is central nervous system cancer.