TRIM21 and neoplasm: However, TRIM21 expression had no significant impact on other clinical characteristics such as age (RR = 1.06; 95% CI: 0.91–1.25; P = .068), sex (RR = 1.04; 95% CI: 0.95–1.12; P = .953), or tumor size (RR = 1.14; 95% CI: 0.97–1.33; P = .05).