In terms of TRIM21 dysregulation, low TRIM21 expression was identified in KIRC (Kidney renal clear cell carcinoma), MESO (Mesothelioma), SARC (Sarcoma), SKCM (Skin Cutaneous Melanoma), READ (Rectum adenocarcinoma) and THCA (Thyroid carcinoma). Here, TRIM21 is linked to cutaneous melanoma.