Tumor negative factor acceptor superfamily member 1A (TNFRSF1A), as an acceptor for TNFSF2/TNF‐alpha and homologous TNFSF1/lipoxin‐alpha, can mediate neuroinflammation and neuronal excitotoxicity,23 and is a high‐risk gene for AD.24 Here, TNFRSF1A is linked to Alzheimer disease.