The median intensity of SARS-CoV-Prot_S1 T-cell responses, assessed by ELISpot IFN-γ assay, was significantly enhanced after COVID-19 vaccination (56.0 SFC/3.105 cells (IQR: [25.8-144.0]) vs 20.0 SFC/3.105 cells (IQR: [12.0-42.8]), p=0.006, Figure 1C). Here, IFNG is linked to COVID-19.