On the other hand, Atp8a2 gene, a selective microglial marker (117), and other genes related to tolerogenic and anti-inflammatory processes in MG and EAE such as DVL-1 (64, 65) and Dusp5 (61, 62) were up-regulated by IFN-γ in CX3CR1highPD-L1low MG. Here, ATP8A2 is linked to myasthenia gravis.