BMP4 protein degradation, Protein degradation, Mature neuropeptide substrates degradation, lysosomal degradation of pre-hormones, Pro-granzyme B in cytotoxic lymphocytes processing, Active peptide neurotransmitters production, Angiogenic switching, Tumor vasculature regulating, Colorectal, Pancreatic, Prostate cancer, Glioma, Melanoma, Breast cancer, Fibrous meningioma, Arthritis, Lung cancer. This evidence concerns the gene BMP4 and Familial prostate cancer.