BMP4 protein degradation, Protein degradation, Mature neuropeptide substrates degradation, lysosomal degradation of pre-hormones, Pro-granzyme B in cytotoxic lymphocytes processing, Active peptide neurotransmitters production, Angiogenic switching, Tumor vasculature regulating, Colorectal, Pancreatic, Prostate cancer, Glioma, Melanoma, Breast cancer, Fibrous meningioma, Arthritis, Lung cancer. The gene discussed is BMP4; the disease is arthritic joint disease.