To explore the relationship between IFN-γ and the expression of immune checkpoints, the correlation between IFN-γ and CD47, IDO1, and PD-L1 was detected from the TCGA database, and it was found that IFN-γ had positive correlation responses with all of them in HCC (Figures 1B–D). This evidence concerns the gene IFNG and hepatocellular carcinoma.