The biological functions of VEGF after binding to receptors involve tumor angiogenesis (VEGF-A, PlGF), new blood vessels maintenance (VEGF-B), lymphangiogenesis and angiogenesis (VEGF-C), generation (VEGF-C/D), vascular permeability (VEGF-A/C), chemotaxis (VEGF-A, PlGF), migration (VEGF-A, PlGF), differentiation (VEGF-D), and survival (VEGF-A/B/C, PlGF) (17). The gene discussed is PGF; the disease is neoplasm.