Not only do we reproduce the finding by the Mobbs lab of more profound hypoglycemia (at 30 min) for the “Recurrent Hypo” group (vs. the “1X Hypo” group), but also we describe attenuated rises of CRR hormones – here, glucagon and epinephrine at 30 min after the 5th insulin injection vs. glucagon and corticosterone at 4 hrs after the 5th insulin injection in (42). The gene discussed is GCG; the disease is Hypoglycemia.