Recent findings suggest that PPARG can affect a variety of biological functions by regulating and expressing different signaling pathways, such as β2-adrenaline promoting of BC growth and angiogenesis through the downregulation of PPARG [51], and as a PPARγ agonist, VSP-17 is capable of inhibiting the process of EMT, thereby suppressing the migration and invasion of triple-negative BC cells, through the PPARG/AMPK signaling pathway [52]. The gene discussed is PPARG; the disease is breast cancer.