Another study, investigating weight loss in presurgical PCa patients, found weight loss‐induced mixed effects on tumour gene expression, with increased expression of the proliferative marker Ki67 in malignant epithelium as well as reduced expression of genes related to insulin secretion (EFNA5), and increased expression of immune response genes (MRC1, HLA‐PB1 and CD86) and DNA repair genes.27 The gene discussed is INS; the disease is neoplasm.