CD79A and irritable bowel syndrome: Probiotics can also inhibit pathogen adhesion to intestinal epithelium by producing bacteriocins and SCFAs; improve the barrier function of intestinal mucosa by increasing mucus layer and producing tight junction proteins; stimulate the production of secretory IgA to improve intestinal immunity, and then relieve metabolic diseases and intestinal disorders diseases such as IBD, IBS and colorectal cancers (Sendid et al., 2009; Eslami et al., 2019; Simon et al., 2021).