MAPT and Alzheimer disease: After three months, cases showed better results in the MMSE and AD assessment scale-cognitive subscale 11-item (ADAS-COG-11), higher concentrations of ACh and 5-HT, lower serum levels of markers of oxidative stress and inflammation, Aβ-42 and p-tau, a higher level of glutathione and changes in gene expression of peripheral blood lymphocytes (Mohamed et al., 2019).