- Reduced memory impairment in both LF groups shown as longer exploration time (p <0.05) and higher preference index (p <0.05) - In ELISA decreased level of soluble and insoluble Aβ in both LF groups in Cortex and hippocampus (p <0.05) - In western blot decreased level of BACE1 (p <0.05, p <0.05), sAβPPβ (p <0.05, p <0.001) and CTFβ (p <0.05, p <0.001) and increased level of sAβPPα (p <0.05, p <0.05), extracellular APOE (p <0.01, p<0.05) and ABCA1 (p <0.05, p <0.05) in both LF groups. The gene discussed is ABCA1; the disease is memory impairment.