CD4 and tuberculosis: Nevertheless, the positive result rate of the QFT-GIT assay was significantly higher in the TB/HIV co-infected patients with CD4+ T cell counts > 350 cells/μL than those in the patients with CD4+ T cell counts < 350 cells/μL (≤ 100 cells/μL vs.> 350 cells/μL: P = 0.020; 101-200 cells/μL vs.> 350 cells/μL: P = 0.009; 201-350 cells/μL vs.> 350 cells/μL: P = 0.037), indicating that CD4+ T cells exhaustion had a significant impact on the outcome of the QFT-GIT assay.