also reported that although IP-10 protein as a target yielded a slight higher positive result rate than that IFN-γ as a target in the non-TB patients with HIV infection, there were no significant differences between the use of IP-10 and IFN-γ as a target either in individuals with a higher risk of M.tb infection (IP-10 40.0%vs. IFN-γ 37.5%) or in individuals with a lower risk of M.tb infection (IP-10 12.9%vs. IFN-γ 4.8%) (Vanini et al., 2012). Here, IFNG is linked to HIV infectious disease.