In four main subtypes of breast cancer, elevated expression of BMPR1B and ACVR2B were seen in Luminal A subtype, while BMP4, GDF15 and ACVR1B were higher in Luminal B, TGFBR1 and BMP8A were higher in HER2 positive, BMP2, BMP6 and GDF5 were higher in TNBC. This evidence concerns the gene ACVR2B and breast carcinoma.