In the current study, a total of 17 genes with prognostic values have been identified, of which 8 genes (SFXN5, LRRC8E, KCNJ10, UPB1, SLC43A2, SLC38A10, ACCS, and SLC38A5) were identified for the first time in pancreatic cancer. This evidence concerns the gene LRRC8E and familial pancreatic carcinoma.