Examples include IFI6, IL1B, CCL4, IDO1, GBP5, IRF1, JAK3, UBD, CXCL5, CCL20, VDR, CD80, IFI44L, NLRP3, and IL7R, several of which were previously implicated in TB pathogenesis (37). The gene discussed is NLRP3; the disease is tuberculosis.